Automated Motif Discovering in Rna Molecules
نویسنده
چکیده
We used a novel graph-based approach to identify recurrent RNA tertiary motifs embeddedwithin secondary structure. We catalogued all the secondary structural elements of the RNA molecule and clustered them using an innovative graph similarity measure. We applied our method to three widely studied structures: H.m 50S, E.coli 50S and T.th 16S. We identified 10 known motifs without any prior knowledge of their shapes or positions. We additionally identified four putative new motifs.
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